日本ウォーターズ（米国本社 Waters Corporation）　 Official site

The structural analysis of by-products and unknown impurities in organic synthesis is an extremely important process in various fields such as pharmaceuticals, pesticides, food, and chemistry. The necessity for this analysis is increasing year by year due to the need for quality improvement of products, including impurity profiling in pharmaceuticals and pesticides, the trend of regulatory strengthening in the health food sector, and the impact of trace impurities on the quality of chemical products. Generally, structural analysis widely utilizes methods such as NMR after separation and purification; however, these methods pose challenges due to the significant time and effort required. Against this backdrop, there is a growing demand for rapid and high-precision analytical methods that complement traditional techniques. In this webinar, we will introduce a comprehensive profiling analysis workflow for synthetic by-products and impurities using the SmartMS - ACQUITY RDa mass spectrometer, which incorporates innovative technology and completely eliminates the complexities of high-resolution mass spectrometry, along with the waters_connect UNIFI software, which excels in large-scale data analysis. Participants will experience the latest solutions through demonstrations of the software.

Twenty years have passed since Waters launched the world's first ultra-high-performance liquid chromatograph (UPLC), and with the inclusion of <2.00> General Principles of Chromatography in the Japanese Pharmacopoeia, more people are becoming interested in speeding up LC analytical methods. On the other hand, we hear voices saying, "I understand the benefits, but it's difficult to adopt it for quality control methods in the current situation," and "I don't know what other applications there are besides adopting it for quality control methods." In this webinar, we will focus on the development of analytical methods among the various applications of high-speed and high-resolution analysis, explaining the transfer of analytical methods from UPLC to HPLC, points for column selection, and the differences between HPLC and UPLC systems.

We are currently holding a nitrosamine analysis observation event year-round at our Tokyo headquarters and Osaka branch showrooms. After confirming your preferred date, we will adjust the schedule and generally guide one group per day. Please send the following necessary information via the inquiry form on this page to apply: ■ Preferred venue (Tokyo or Osaka) ■ Preferred date - First choice ■ Preferred date - Second choice ■ Expected number of participants (up to 5 people) ■ Other requests By clicking [Send], you are deemed to have agreed to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

What is an efficient separation method development approach for the analysis of nitrosamines? Nitrosamines in pharmaceuticals are a health risk even at extremely low concentrations and are subject to regulation in various countries. In Japan, the Ministry of Health, Labour and Welfare issued a notification in 2021, mandating that measures must be taken by August 1, 2025. As ongoing quality testing is expected, the establishment of a reliable analytical system is required. However, nitrosamines are impurities that require trace-level and highly sensitive detection, and the establishment of advanced separation techniques (separation methods) that are not influenced by the active ingredients or excipients is key. In this seminar, we will explain: - Key points for global regulatory compliance - Development approaches for separation methods essential for trace impurity analysis - Features of devices equipped with ZSpray structures that excel in maintainability and contamination resistance We will provide a practical demonstration. If you are considering the introduction or update of equipment, or if you have challenges with the sensitivity and accuracy of impurity analysis, please join us. 【Title】 Nitrosamine Analysis Observation Meeting: How to streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? ~Introducing approaches for developing separation conditions~

In environments where HPLC is used regularly, there are concerns such as "the workforce is fluid and skills do not settle," "we want to streamline and improve the efficiency of examining analytical conditions," and "it takes time to select columns each time." Additionally, there are many HPLC devices and analytical columns available, making it difficult to determine what is the "easiest HPLC to use" for ourselves. Therefore, in this webinar, we will clearly explain practical information such as the characteristics of different HPLC models, the latest devices that pursue "ease of use," and how to choose columns based on analytical purposes. This content is also recommended for those who want to elevate their level of HPLC utilization or are considering selection and review in the future. Please take this opportunity to check out the know-how that can be immediately applied to your daily operations.