Low Adsorption UPLC System ACQUITY Premier
Solving non-specific sample adsorption! Improved peak shape and sensitivity with new technology, featuring low adsorption and bio-inert LC with excellent reproducibility and durability.
The ACQUITY Premier system incorporates the new MaxPeak High Performance Surfaces (HPS) technology, which effectively reduces sample loss due to nonspecific adsorption caused by interactions with metals, while providing the following benefits: ■ Ideal for the analysis of organic acids, organophosphates, oligonucleotides, peptides, glycoproteins, phospholipids, veterinary drugs, chelating agents, and more. ■ Improved sensitivity and reduced risk of peak omission. ■ Elimination of column and system passivation and conditioning, saving time and costs. ■ Enhanced reproducibility and reliability of results. A variety of low-adsorption columns featuring MaxPeak High Performance Surfaces (HPS) technology are also available. When used in combination with the system, they enable more reliable analyses. *We also offer online briefings and demonstrations, so please feel free to contact us.
basic information
This is a new LC system that maintains the high-speed and high-separation chromatography performance of UPLC while thoroughly reducing metal adsorption. By connecting it as an inlet to optical detectors or high-resolution MS, it prevents the loss of target components.
Price information
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Applications/Examples of results
- Significant improvement in sensitivity, peak shape, and recovery rates for phospholipids and carboxylic acid-type lipids. - Enhanced analytical sensitivity and chromatographic peak shape in the quantification of compounds constituting the TCA cycle in human plasma. - Avoidance of passivation treatment in phosphopeptide analysis. - High selectivity and high sensitivity LC-MS to support research and development of oligonucleotide therapies. - Improvement of LC-MS/MS analysis of B vitamins using MaxPeak High Performance Surfaces technology.
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Key Points for Method Development Using UPLC and Transfer to HPLC - Live Webinar on August 21
Twenty years have passed since Waters launched the world's first ultra-high-performance liquid chromatograph (UPLC), and with the inclusion of <2.00> General Principles of Chromatography in the Japanese Pharmacopoeia, more people are becoming interested in speeding up LC analytical methods. On the other hand, we hear voices saying, "I understand the benefits, but it's difficult to adopt it for quality control methods in the current situation," and "I don't know what other applications there are besides adopting it for quality control methods." In this webinar, we will focus on the development of analytical methods among the various applications of high-speed and high-resolution analysis, explaining the transfer of analytical methods from UPLC to HPLC, points for column selection, and the differences between HPLC and UPLC systems.
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How can we streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? Nitrosamine Analysis Workshop [Tokyo, Osaka]
We are currently holding a nitrosamine analysis observation event year-round at our Tokyo headquarters and Osaka branch showrooms. After confirming your preferred date, we will adjust the schedule and generally guide one group per day. Please send the following necessary information via the inquiry form on this page to apply: ■ Preferred venue (Tokyo or Osaka) ■ Preferred date - First choice ■ Preferred date - Second choice ■ Expected number of participants (up to 5 people) ■ Other requests By clicking [Send], you are deemed to have agreed to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy
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[On-Demand Webinar] Improving Data Quality and Operational Efficiency with Low Adsorption LC - Welcome to a New Era of Chromatography -
Due to the diversification and complexity of analysis targets, as well as changes in modalities, HPLC is required to have a higher level of robustness, reproducibility, flexibility, and convenience. Particularly in the analysis of compounds that are susceptible to metal influences, unpredictable sample loss can sometimes occur, making rapid and accurate data analysis difficult and potentially impairing operational efficiency. In this live webinar, we will introduce cases where the analysis results of samples that tend to adsorb metals have significantly improved by using the newly designed Arc Premier HPLC system and Premier columns, which reduce sample adsorption. By avoiding various risks associated with measuring adsorbent samples and improving data quality, we promote increased sample throughput, reduced analysis costs, and enhanced laboratory operational efficiency. Target Audience: - Those struggling with the measurement of samples that tend to adsorb metals - Those looking for low-adsorption LC systems and columns
