Soft Ionization Technology 'APGC' Without Helium Gas
Are you having trouble procuring helium gas for GC-MS analysis? Achieve high-sensitivity analysis without being affected by carrier gas.
APGC (Atmospheric Pressure Gas Chromatography) is a soft ionization technology that features excellent ionization efficiency and high sensitivity. It allows for a quick and easy switch of the MS inlet system from LC to GC without releasing the vacuum. Due to the absence of vacuum constraints, a wider range of GC columns and carrier gas flow rates can be utilized, maximizing the functionality of GC. 【Features】 ■ APGC ion source unaffected by carrier gas ■ Avoids sensitivity loss due to fragmentation ■ Operates stably for long periods without ion burn *For more details, please refer to the PDF document or feel free to contact us.
basic information
【Other Features】 ■ Connection to GC is possible for all Waters universal ion source-based systems ■ Soft ionization technology with excellent ionization efficiency and high sensitivity ■ Quick and easy switching of the MS inlet system from LC to GC ■ No vacuum limitations ■ A wider range of GC columns and carrier gas flow rates can be used ■ Maximizes the functionality of GC ■ LC and GC on a single MS platform ■ Extended features ■ Improved flexibility in chromatography ■ Other carrier gases ■ High levels of sensitivity achievable with Xevo TQ-XS *For more details, please refer to the PDF document or feel free to contact us.
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Applications/Examples of results
【Usage】 ■Mass Spectrometry *For more details, please refer to the PDF document or feel free to contact us.
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The APGC ion source equipped with the soft ionization method developed by Waters achieves high sensitivity and high selectivity compared to conventional EI methods, significantly expanding the scope of quantitative analysis using GC-MS. Furthermore, there is no decrease in sensitivity even when changing the carrier gas from helium to nitrogen, making it an effective measure against helium shortages. Additionally, it allows for the direct analysis of acetonitrile solutions after QuEChERS purification with low injection volumes, providing practical advantages such as improved efficiency in sample preparation and prevention of loss of low-boiling compounds. In this webinar, Waters' analytical chemists will introduce the features of APGC and its application in pesticide residue analysis, while also inviting customers who are active in the front lines of analytical work to share practical insights on simplifying sample preparation and reducing maintenance through increased sensitivity. ■ Target Audience Individuals engaged in high-sensitivity pesticide residue analysis using GC-MS, those considering the efficiency of sample preparation processes, and those interested in the use of alternative gases to helium. ■ Program Overview of the APGC ion source and explanation of comparisons and differences with the EI method; introduction of APGC features and examples of pesticide residue analysis from the user's perspective.
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Cosmetics & Personal Care Application Note Collection
Waters provides numerous innovative technologies to leading companies in the global cosmetics and personal care products industry to improve the efficiency of inspections related to raw materials, ingredients, safety, and quality control. By leveraging our continuously advancing sample preparation products, columns, chromatography, mass spectrometry systems, and data management software, it becomes possible to shorten analysis time in analytical labs, enhance data quality, reduce costs, and comply with requirements in an ever-changing regulatory environment. - Ingredient composition ratios and safety verification in lotions, emulsions, and foundations - Evaluation of functional ingredients that provide high moisture retention and whitening effects - Assessment of container packaging degradation and concerns regarding leachables If you are facing challenges with the analyses mentioned above, please contact us.
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Waters Corporation, headquartered in Milford, Massachusetts, USA, has played a pioneering role as a specialized manufacturer of liquid chromatography since its establishment in 1958. Actively engaged in the development of new products and technologies, it has grown into an international group company that supplies not only high-performance liquid chromatography but also mass spectrometers (MS) and thermal analysis instruments. Waters Japan started operations in 1973 (Showa 48) as the Japanese base of Waters Corporation. Inheriting the corporate ethos of the U.S. headquarters, we have made "Customer Success" our mission and continue to provide innovative technologies and lab solutions.