Low Adsorption UPLC System ACQUITY Premier
Solving non-specific sample adsorption! Improved peak shape and sensitivity with new technology, featuring low adsorption and bio-inert LC with excellent reproducibility and durability.
The ACQUITY Premier system incorporates the new MaxPeak High Performance Surfaces (HPS) technology, which effectively reduces sample loss due to nonspecific adsorption caused by interactions with metals, while providing the following benefits: ■ Ideal for the analysis of organic acids, organophosphates, oligonucleotides, peptides, glycoproteins, phospholipids, veterinary drugs, chelating agents, and more. ■ Improved sensitivity and reduced risk of peak omission. ■ Elimination of column and system passivation and conditioning, saving time and costs. ■ Enhanced reproducibility and reliability of results. A variety of low-adsorption columns featuring MaxPeak High Performance Surfaces (HPS) technology are also available. When used in combination with the system, they enable more reliable analyses. *We also offer online briefings and demonstrations, so please feel free to contact us.
basic information
This is a new LC system that maintains the high-speed and high-separation chromatography performance of UPLC while thoroughly reducing metal adsorption. By connecting it as an inlet to optical detectors or high-resolution MS, it prevents the loss of target components.
Price information
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Applications/Examples of results
- Significant improvement in sensitivity, peak shape, and recovery rates for phospholipids and carboxylic acid-type lipids. - Enhanced analytical sensitivity and chromatographic peak shape in the quantification of compounds constituting the TCA cycle in human plasma. - Avoidance of passivation treatment in phosphopeptide analysis. - High selectivity and high sensitivity LC-MS to support research and development of oligonucleotide therapies. - Improvement of LC-MS/MS analysis of B vitamins using MaxPeak High Performance Surfaces technology.
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"One Rank Higher LC Application Seminar" to Help Improve Analysis Accuracy - A Total of 6 Sessions Held [Live Webinar]
[Viewer Benefits Available] Explaining Tips for LC in a Short Seminar Do you have concerns such as "I'm unsure about column selection," "I'm struggling to optimize analysis conditions," or "I have challenges analyzing compounds with weak retention" in LC analysis? Waters will hold a seminar titled "Must-Listen! Advanced LC Application Seminar" where you can learn practical LC analysis know-how in just 30 minutes. In this seminar, we will cover useful topics in a total of six sessions, including tips for choosing detectors, how to utilize reverse phase columns, scaling up to preparative LC, approaches for analyzing hydrophilic and highly polar compounds, case studies of low-adsorption HPLC, and improving purity through solid-phase extraction. Each session is scheduled to start at 15:00. Event Themes: • October 6 (Tuesday) - Session 1: Tips for Choosing Detectors • October 13 (Tuesday) - Session 2: Tips for Choosing Columns • October 21 (Wednesday) - Session 3: Tips for Preparative LC • October 27 (Tuesday) - Session 4: Approaches for Analyzing Hydrophilic and Highly Polar Compounds • November 5 (Tuesday) - Session 5: Case Studies of Low-Adsorption HPLC • November 10 (Tuesday) - Session 6: Tips for Solid-Phase Extraction
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How can we streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? Nitrosamine Analysis Workshop [Tokyo, Osaka]
We are currently holding a nitrosamine analysis observation event year-round at our Tokyo headquarters and Osaka branch showrooms. After confirming your preferred date, we will adjust the schedule and generally guide one group per day. Please send the following necessary information via the inquiry form on this page to apply: ■ Preferred venue (Tokyo or Osaka) ■ Preferred date - First choice ■ Preferred date - Second choice ■ Expected number of participants (up to 5 people) ■ Other requests By clicking [Send], you are deemed to have agreed to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy
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[On-Demand Webinar] Improving Data Quality and Operational Efficiency with Low Adsorption LC - Welcome to a New Era of Chromatography -
Due to the diversification and complexity of analysis targets, as well as changes in modalities, HPLC is required to have a higher level of robustness, reproducibility, flexibility, and convenience. Particularly in the analysis of compounds that are susceptible to metal influences, unpredictable sample loss can sometimes occur, making rapid and accurate data analysis difficult and potentially impairing operational efficiency. In this live webinar, we will introduce cases where the analysis results of samples that tend to adsorb metals have significantly improved by using the newly designed Arc Premier HPLC system and Premier columns, which reduce sample adsorption. By avoiding various risks associated with measuring adsorbent samples and improving data quality, we promote increased sample throughput, reduced analysis costs, and enhanced laboratory operational efficiency. Target Audience: - Those struggling with the measurement of samples that tend to adsorb metals - Those looking for low-adsorption LC systems and columns
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Waters Corporation, headquartered in Milford, Massachusetts, USA, has played a pioneering role as a specialized manufacturer of liquid chromatography since its establishment in 1958. Actively engaged in the development of new products and technologies, it has grown into an international group company that supplies not only high-performance liquid chromatography but also mass spectrometers (MS) and thermal analysis instruments. Waters Japan started operations in 1973 (Showa 48) as the Japanese base of Waters Corporation. Inheriting the corporate ethos of the U.S. headquarters, we have made "Customer Success" our mission and continue to provide innovative technologies and lab solutions.