Dynamic and Static Light Scattering Detector DynaPro NanoStar 2
Easy-to-use dynamic/static light scattering (DLS/SLS) measuring instrument - Conveniently and quickly measures particle size distribution, particle concentration, stability, and molecular weight.
The DynaPro NanoStar 2 supports both dynamic light scattering (DLS) and static light scattering (SLS) measurements, allowing for the measurement of particle size distribution, particle concentration, interactions (kD, A2), and weight average molecular weight (Mw) of nanoparticles and proteins. It can be used for the analysis of proteins, gene therapy vectors, viruses and virus-like particles, indiscriminate inhibitors, micelles, liposomes, LNPs (lipid nanoparticles), and metal nanoparticles. To accommodate rare and precious samples, the specially designed quartz cuvette provides robust and accurate measurements with just 2 µL of solution. 【Features】 - Supports both dynamic light scattering (DLS) and static light scattering (SLS) measurements - Easy operation with an intuitive touchscreen - Achieves a wide range of temperature settings (-10 to 120°C) and fast temperature gradient settings - Connects with the multi-angle light scattering detector DAWN to support flow DLS measurements - Abundant cell options (2μL capacity quartz cell, 4μL capacity disposable cell, commercially available 4mL quartz cell, disposable cell (using adapter))
basic information
A dynamic and static light scattering measurement device useful for the characterization of proteins, nanoparticles, colloids, and polymers, capable of performing the following measurements: - Hydrodynamic radius (Rh), particle size distribution, particle concentration - Weight average molecular weight (Mw) - Aggregate and stability parameters (Tm, Tagg, kD, A2)
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Applications/Examples of results
- Determination of the conformation and aggregation number of biomolecules - Detection and quantification of protein aggregates - Estimation of physical viral titer - Evaluation of thermal, colloidal, and stereochemical stability of biopharmaceuticals - Measurement of diffusion interaction parameter kD and second virial coefficient - Measurement of particle size and concentration of liposomes and emulsions - Stability evaluation of nanoemulsions - Detection of aggregates of compounds - Evaluation of solubility of polymers - Detection of purity or contaminants
