Cosmetic ingredient Elastin for elasticity improvement with reconstructed pentapeptide Elacelf.
A pentapeptide synthesized by mimicking the fragment of MFAP4. It recognizes damage, stimulates the production of MFAP4, and reconstructs elastin.
Elaself is a pentapeptide (valine-serine-glycine-isoleucine-arginine) synthesized to mimic a fragment of MFAP4. MFAP4 is necessary for binding fibrillin chains to form microfibrils. These microfibrils are then further modified to become mature elastic fibers (elastin). <In Vitro> MFAP4 gene expression (+30%) Collagen type I gene expression (+30%) Increased intracellular collagen levels in NHDF cells (20-60%) Increased elastin levels <In Vivo> Improvement in skin elasticity (R2: 20%, R5: 25%) Reduction in wrinkle depth (-40%)
basic information
Contipro is a biotechnology company and a global manufacturer of active ingredients used in the pharmaceutical and cosmetics industries for nearly 30 years. We offer a range of products including sodium hyaluronate and its derivatives produced by fermentation, as well as distinctive peptides and natural polysaccharides.
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Applications/Examples of results
Recommended blending amount: 0.01 – 1% It is recommended to add during the cold process.
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