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Efficient polishing purification of antibody drugs: "Cellufine MAX IB"

Mixed-mode chromatography resin that can be used for polishing purification after protein A chromatography.

"Cellufine MAX IB" is a new mixed-mode resin used for the polishing purification of monoclonal antibodies (Mab) after the purification of Protein A resin. It features surface modification with polyallylamine and the modification of some parts with butyl groups, allowing proteins to adsorb even at high salt concentrations. 【Features】 ■ Can be used for the polishing purification of antibody drugs ■ After Protein A purification, it can achieve high purity with just one purification step ■ Contributes to reduced lead times and cost savings through a two-step purification process ■ Stable resin that allows for in-place cleaning with 0.5M sodium hydroxide ■ Unique salt tolerance that retains proteins even at high salt concentrations *For more details, please refer to the PDF document or feel free to contact us.

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basic information

【Other Features】 Base resin: Highly cross-linked cellulose particles Average Diameter: Average 90 µm Ligand: Polyallylamine, partially modified with butyl groups Ion Exchange Capacity: > 80 μeq/mL Clean-in-Place (CIP): 0.5 M NaOH Sterilization: Autoclave at 121 °C, 20 min Recommended Cleaning Conditions: Ethanol (70%), Isopropanol (30%), Guanidine HCl (6M), Urea (6M) *For more details, please refer to the PDF document or feel free to contact us.*

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Applications/Examples of results

For more details, please refer to the PDF document or feel free to contact us.

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Chromatography packing material "Cellfine"

PRODUCT

Technical Data Sheet: "Cellfine MAX IB" for Polishing Purification of Antibody Drugs

TECHNICAL

Technical Data Sheet: Column Packing Example for Virus Purification Chromatography "Cellfine Sulfate"

TECHNICAL

[Usage Example] Purification Case of Influenza Virus 'Cellfine Sulfate' (English Version)

TECHNICAL

Technical Data Sheet: Chromatography for Virus Purification "Cellfine Sulfate"

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Technical Data Sheet: Endotoxin Removal Chromatography 'Cellfine ET Clean'

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[Technical Column] Purification of Monoclonal Antibodies from CHO Cell Culture Supernatant Using Cellfine

TECHNICAL

[Technical Data Sheet] Purification of Antibody Drugs with 'Cellfine SPA-HC'

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【Technical Data Sheet】Purification of Antibody Drug Aggregates using 'Cellfine MAX GS'

TECHNICAL

[Catalog] Purification of Antibody Drug Aggregates 'Cellfine MAX GS' (English Version)

TECHNICAL

Technical Data Sheet: Comparison of Selfine Cation Exchange Chromatography (English Version)

TECHNICAL

[Technical Column] An Efficient Method for Purifying Monoclonal Antibodies Using Selfine in Flow-Through Mode

TECHNICAL

[Technical Column] Two-Step Purification of Monoclonal Antibodies Using Cellfine

TECHNICAL

[Technical Column] A Case Study on the Purification of Human Coronavirus OC43 Using Selfine Sulfate

TECHNICAL

[Technical Column] A Case Study on the Purification of T7 RNA Polymerase Using Selfine Phosphate

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