Utilization of MFC in Biopharmaceutical Manufacturing 1
ITWジャパン
In the manufacturing process of active pharmaceutical ingredients for biopharmaceuticals, including antibody drugs and vaccines, the goal is to culture and scale up biological entities such as viruses and cells, necessitating the creation of an environment conducive to the survival of the target organisms. The research and development department continuously seeks the optimal conditions for each type of cell or virus, which involves adjusting the flow rates of air, oxygen, nitrogen, and carbon dioxide to achieve optimal concentrations. Additionally, it is crucial to maintain a stable environment by adjusting the flow rates of each gas in response to monitoring results of pH and dissolved oxygen concentration. Particularly for oxygen, even small flow rates can lead to a rapid increase in dissolved oxygen concentration, requiring precise control of the flow rates. The SLA5800 series has a proven track record in many culture devices and facilities, continuing from the previous generation 5800E/i series, and is a stable product line with a large number of units shipped and consistent maintenance continuity. ITW Japan Co., Ltd. Brooks Instrument
