Participation in this webinar has ended. Those who wish to access the on-demand version can register for details and viewing. Contaminated regenerative medicine products and gene therapy products (Advanced Therapy Medicinal Products: ATMP) pose a risk to the lives of patients receiving treatment. The current international pharmacopoeia requires 14 days for sterility testing, but the typical shelf life of an ATMP is 48 hours. We have developed a qPCR testing method that can detect bacterial and fungal contamination in just under 3 hours before treatment begins. In this webinar, we will present a validation study designed to evaluate the detection capabilities of bacteria and fungi in accordance with EP 5.1.6, USP <1223>, and <1071>. [Related Homepage] https://www.sartorius.com/en/applications-jp/quality-control-testing-jp/microbiological-quality-control-jp/rapid-testing-jp/bacterial-detection-jp

Participation in this webinar has ended. Those who wish to view it on demand can register for details and access after registration. The COVID-19 vaccine demonstrates the potential of the mRNA-based platform; however, so far, manufacturers have primarily focused on the safety and efficacy of mRNA vaccines and have not placed much emphasis on optimizing future production and purification processes. In this webinar, experts will discuss the current approaches and bottlenecks in mRNA production and will hold a panel discussion on the vision for optimized next-generation processes. Key learning objectives: • The real challenges in mRNA manufacturing and Sartorius's efforts to develop innovative solutions in collaboration with customers • The importance of flexibility in mRNA purification • Introduction to rapid analytical monitoring methods for IVT reactions using CIMac PrimaS Thursday, May 27 Session 1: 16:00 - 17:00 Session 2: 23:30 - 24:30 (ends at 0:30 on May 28)

The main purpose of cryopreservation is to preserve biological specimens. This technique is very important for biotechnology. However, the freezing-thawing process puts stress on all cells and tissues. In this webinar, we will explain how to overcome these challenges, address issues related to survival rates after cryopreservation, and provide safe and efficient methods for cell cryopreservation. Topics: • Basics and limitations of cryopreservation • Selection of cryopreservation media • Troubleshooting • Safety tips and considerations Even if you cannot attend the live broadcast, please register first. Those who register will receive a link to the on-demand archive. Instructor Introduction Oren Ben-Yosef, PhD Bachelor of Science in Biotechnology Engineering from the Technion - Israel Institute of Technology, and a Doctor of Medicine. Focused on the culture methods and differentiation of embryonic stem cells and induced pluripotent stem cells. Biological Industries and Sartorius will continue to develop a strategic partnership in chemical technology for cell therapy and regenerative medicine. We will continue to provide high-performance stem cell-related products to sustain the benefits gained over the coming years.

Registration for this webinar has ended. Those who wish to access the on-demand version can register for details and viewing. How scalable and intensified is your CAR-T process In this webinar, Dr. Qasim Rafiq, Associate Professor of Cell and Gene Therapy Bioprocess Engineering at University College London, will introduce the process control strategies developed to improve CAR-T yield. Webinar Overview: - Consistent scalable expansion of CAR-T cells in stirred-tank bioreactors - Reduction of variability - Establishment of management strategies for enhancing the CAR-T process

Participation in this webinar has ended. Those who wish to view it on demand can register for details and access it after registration. James Edwards, a product development scientist specializing in automated cell culture technology, and Donald Traul, a senior field application specialist, will give a presentation based on the following propositions using actual examples of Ambr 15 and Ambr 250: - Efficient clone selection - Screening of optimal media and feed media - Optimization of process parameters in simulated perfusion or perfusion - The fastest route to high-density cell culture processes

Participation in this webinar has ended. Those who wish to view it on demand can register through the details and application section. Priyanka Gupta, Head of Market Entry Strategy in the protein-based therapy field, will review the industry's needs for process enhancement and consider steps to determine optimal enhancement strategies. Key Learning Objectives: - Identify modular and scalable solutions that can increase productivity by up to four times in both upstream and downstream processes. - Learn how to reduce upfront investment costs by 50% and increase annual product revenue by nearly 50%. - Discover data analytics and automation tools that provide robust process control and significantly impact product cost and quality. Cost-conscious biopharmaceutical manufacturers and CDMOs are facing increasing pressure to accommodate various modalities and batch sizes. Process enhancement is a logical solution. We will help you determine where and how to enhance your processes in the following ways: - Improving productivity - Reducing cost of goods sold (COGS) - Increasing flexibility - Reducing footprint - Shortening timelines

Participation in this webinar has ended. Those who wish to view it on demand can register through the details and application section. In this webinar, the head of protein-based therapeutics will identify the industry's enhanced processing needs, explore solutions using a decision criteria matrix, and determine the optimal enhancement strategy. Discover modular and scalable upstream and downstream solutions that can lead to up to a 4-fold increase in productivity. We will guide you to modular and scalable solutions that can reduce capital investment costs by 50% and increase productivity by four times. You can find data analytics and automation tools that provide robust process control, significantly impacting product and quality costs.

We will hold three webinars in March. - March 11 at 12:00 AM | Integrated mRNA production process from E. coli to highly purified mRNA - March 24 at 12:00 AM | Virtual demo and overview of the BioSMB multi-column chromatography platform - March 30 at 5:00 PM & March 31 at 12:00 AM | Extractables Assessments (with ExSim) - sessions will be split into two parts For customers who cannot attend the webinars, an on-demand version will also be available. Please check the attached file or the displayed URL for more details.

Participation in this webinar has ended. Those who wish to view it on demand can register through the details and application section.