Toolbox for the development of oligonucleotide therapeutics and nucleic acid medicines.
LGC, Biosearch Technologies supports advancements in the nucleic acid pharmaceuticals industry with reagents and equipment for nucleic acid synthesis!
LGC Biosearch Technologies (hereinafter referred to as LGC Biosearch) supports the development of nucleic acid medicines with a diverse portfolio that includes oligonucleotide modifiers, solid-phase support carriers, and other reagents. LGC Biosearch products are used in the manufacturing and development of over 100 approved or in-development therapeutics, with at least one product being utilized in each. LGC Biosearch simplifies the journey from drug discovery to commercialization through reliable technical support and industry-leading products.
basic information
■Sugar phosphate backbone modifiers and other modifiers ●Locked nucleic acids (LNA) ●Peptide nucleic acids (PNA) ●Alkyl phosphoramidites ●H-phosphonates ●Sulphurising reagents ●Vinyl phosphonates ■Modifications for nuclease resistance enhancement ●3′-DNA ●AlkA ●Dideoxy ●2′-F solid supports ●2′-OMe solid supports ●Reverse synthesis solid supports ●2′-F phosphoramidites ●2′-OMe phosphoramidites ●Reverse synthesis phosphoramidites ■Modifications for cell delivery and uptake ●Lipophilic modifiers ●GalNAc modifiers ●Vitamin modifiers ■Solid phase support carriers
Price range
Delivery Time
Applications/Examples of results
As a partner in the research and development of nucleic acid pharmaceuticals, LGC Biosearch is developing custom oligonucleotides for nucleic acid drugs. Its extensive product portfolio includes modifications that are essential for optimizing therapeutic efficacy. Additionally, LGC Biosearch has expertise in a wide range of therapeutic processes, including ASO, siRNA, immunostimulatory nucleic acids, aptamers, miRNA and miRNA antagonists, and guide RNA for CRISPR. By combining a long history of supporting the research and development of therapeutic nucleic acids with technical and specialized knowledge, we can address complex challenges related to nucleic acid pharmaceuticals. Furthermore, LGC Biosearch consistently delivers the most reliable products for diverse applications in accordance with ISO quality manufacturing standards.
