Compounds or their metabolites found in pharmaceuticals, cosmetics, and food can have high hydrophilicity. In environmental monitoring, hydrophilic and highly polar compounds may also be targeted in water system environmental analysis. Since these compounds are difficult to analyze using conventional reverse phase chromatography, hydrophilic interaction chromatography (HILIC) is often suitable. On the other hand, many people may think, "It sounds complicated just by the name," and have not yet tried HILIC, or they may not be satisfied with their current HILIC analysis. In this seminar, we will introduce the principles of HILIC analysis, key points for method development, and columns suitable for HILIC analysis. Program: ■ Basics of HILIC mode ■ Development of HILIC analytical methods ■ Columns suitable for HILIC mode and analysis examples Target Audience: ■ Those analyzing highly polar and hydrophilic compounds ■ Those planning to conduct analyses in the future ■ Those considering improvements to their current HILIC analysis

In this live webinar, we will have a presentation from Shionogi Pharma on the high-sensitivity analysis of nitrosamine impurities. ■Target Audience Those developing impurity analysis methods and those involved in quality control analysis.

A clear explanation with examples on how to verify whether the LC system is performing at its intended capacity.

Have you ever struggled with scaling up from analytical to preparative chromatography? Many people may be facing issues such as the chromatogram examined in the analysis not being reproducible, excessive solvent consumption, or a short lifespan of the preparative column. In this seminar, we will explain tips for preparative purification to maximize the load and obtain as many target substances as possible in a single purification, using analytical examples. Program: ■ Workflow of preparative purification ■ How to determine preparative conditions ■ Tips for selecting preparative columns ■ Introduction of examples of preparative purification

A clear explanation of the QuEChERS method suitable for simultaneous analysis.

An explanation with examples of technology that can streamline and simplify the entire process from extraction to measurement in analysis, based on the fundamentals of two-dimensional LC.

Introducing the disulfide bond mapping feature added to BiopharmaLynx.

Introducing the application of UPLC/Q-Tof MS systems and bioinformatics to routine analysis of the characteristics of antibodies and protein pharmaceuticals.

It's just a vial. Yet, it's a vial. The vial is the component that comes into contact with the sample solution for the longest time. This explains how to choose vials suitable for troubleshooting and analytical techniques derived from vials.

Introduction of actual application examples regarding column selection for retaining highly polar compounds in reversed-phase chromatography.

Introducing the performance of UltraPerformance Convergence Chromatography (UPC2), which achieves ultra-fast, robust, and highly reproducible analysis, along with examples of chiral separation applications.

The Oasis μElution plate enables purification and concentration without the need for evaporation. A new protocol has been developed to further accelerate its throughput.

A discussion on which method is more appropriate for protein expression difference analysis, based on examples of quantified known proteins.

Points for selecting LC columns to improve separation, Part 2. Here, we will focus on column efficiency (N).

This document explains the countermeasures for each step of the solid-phase extraction troubles identified in Sample Preprocessing Troubleshooting Part 1.

We will introduce tips for performing solid-phase extraction and fun experimental examples using dyes for those who are about to start solid-phase extraction.

Starting Here: LC Course ~Intermediate Edition: Efficient Analysis with Chromatographs Tailored to Applications~ When it comes to chromatographs (high-performance liquid chromatography systems), there are various types available depending on their applications. General-purpose analyzers, low-dispersion types, and those with multiple flow paths are just a few examples. The characteristics of a chromatograph significantly influence the analyzable conditions and results. Additionally, using a chromatograph that is not suited for the intended application can lead to inefficiencies, such as prolonged analysis times and unnecessary costs. In this webinar, we will explain the features of each chromatograph, their applications, and their impact on analysis. Program: - Classification of chromatographs - Impact of chromatographs on separation - How to choose a chromatograph based on application

Starting Here: LC Course ~ Beginner's Edition: Basics of LC and Analytical Columns ~ Liquid chromatography (LC) is an essential technology in pharmaceuticals, cosmetics, chemical products, food, environmental fields, and various inspections and tests. On the other hand, you might feel apprehensive, thinking, "Isn't this a complicated technology?" In this webinar, we will explain the basics of LC and the analytical columns that are central to separation. We encourage those who are new to LC to actively participate. Program: - What is chromatography? - Representative separation modes of HPLC - Basics of analytical columns

Introducing a web tool that supports column selection with a focus on selectivity (α) for improving separation in LC column selection.

Rapid and reproducible analysis of high-polarity pesticides without derivatization Waters' Anionic Polar Pesticide Column has been developed to provide a reliable analytical method when combined with Waters UPLC-MS/MS technology. Dedicated columns for applications targeting substances like glyphosate enable excellent retention, peak shape, and separation of a range of anionic polar pesticides without the need for derivatization. We will also introduce the latest tandem quadrupole mass spectrometer used for this analysis. Program - Challenges in the analysis of glyphosate - Introduction of the Anionic Polar Pesticides (APP) column - Challenges (retention, separation, reliability, detection) - Analytical methods and reliability of the APP column - Introduction of the latest tandem quadrupole mass spectrometer