Gene therapy drug analysis column GTxResolve
Improving SEC analysis of proteins, in addition to lipid nanoparticles (LNP), nucleic acids, and viral vectors.
The Waters GTxResolve Premier SEC column enables superior and faster separations by minimizing particle size to the extreme. Additionally, the new HO-PEO bonding reduces both ionic and hydrophobic adsorption, and the stable bonding also achieves noise reduction in MALS. The column tube is treated with MaxPeak technology, eliminating concerns about metal adsorption. 【Features】 - High separation capability allows for the detection of low-concentration impurities, accelerating the analysis of aggregates and size variants. - Provides reproducible data with minimal lot-to-lot and column-to-column variation. - Cost reduction through extended column lifespan. - Reduces secondary interactions and decreases noise in multi-angle light scattering detectors (MALS). - Utilizes low-adsorption hardware necessary for improving the recovery rate of biopharmaceuticals.
basic information
This is an LC column that can be used for size exclusion chromatography (SEC) of mRNA, LNP, viral vectors, and protein pharmaceuticals.
Price information
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Delivery Time
Applications/Examples of results
Analysis of aggregates/size variants of active pharmaceutical ingredients and formulations for gene therapy Evaluation of aggregate content, integrity, heterogeneity, and purity
