High-resolution mass spectrometer (LC-QTof) Xevo G3 QTof
Reliable characteristic analysis - A mass spectrometer that maximizes information about the analysis species.
By using the Xevo G3 QTof, you can maximize the information about the analysis species from samples, enhancing the reliability of results from detailed characterization to accurate quantification. It simplifies and expands the characterization and evaluation of properties, from unstable low molecular weight compounds to complex biopharmaceuticals. By updating the design of the ion optical system and incorporating core technologies that achieve comprehensive quantification capabilities, consistent robustness and performance have been achieved. 【Features】 - Improved permeability of unstable low molecular compounds maximizes coverage of analysis species - Enhanced quantitativeness and expanded dynamic range within and between spectra enable optimal comprehensive quantification/qualitative analysis for screening and target applications - Improvements in the ion optical system lead to a more reliable and robust system - Achieves high levels of accuracy and reproducibility
basic information
Quadrupole - Time-of-Flight Mass Spectrometer (LC-QTof) Equipped with a ZSpray ion source resistant to contamination Adopts StepWave XS ion guide to improve the transmission rate of unstable molecular species Ion source: Multi-mode ion source – Tool-free ESI/APCI/ESCi (standard), APCI, UniSpray, nanoFlow ESI, ASAP, APGC, DESI XS (optional)
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Applications/Examples of results
You can use it for reliable identification of target components in complex matrices across various fields, including structural analysis of biopharmaceuticals and new modalities, as well as impurities in small molecule drugs.
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How can we streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? Nitrosamine Analysis Workshop [Tokyo, Osaka]
We are currently holding a nitrosamine analysis observation event year-round at our Tokyo headquarters and Osaka branch showrooms. After confirming your preferred date, we will adjust the schedule and generally guide one group per day. Please send the following necessary information via the inquiry form on this page to apply: ■ Preferred venue (Tokyo or Osaka) ■ Preferred date - First choice ■ Preferred date - Second choice ■ Expected number of participants (up to 5 people) ■ Other requests By clicking [Send], you are deemed to have agreed to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy
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[Live Demo Available] Nitrosamine Analysis Observation Event | Experience Equipment Tour × Latest Methods in One Day
What is an efficient separation method development approach for the analysis of nitrosamines? Nitrosamines in pharmaceuticals are a health risk even at extremely low concentrations and are subject to regulation in various countries. In Japan, the Ministry of Health, Labour and Welfare issued a notification in 2021, mandating that measures must be taken by August 1, 2025. As ongoing quality testing is expected, the establishment of a reliable analytical system is required. However, nitrosamines are impurities that require trace-level and highly sensitive detection, and the establishment of advanced separation techniques (separation methods) that are not influenced by the active ingredients or excipients is key. In this seminar, we will explain: - Key points for global regulatory compliance - Development approaches for separation methods essential for trace impurity analysis - Features of devices equipped with ZSpray structures that excel in maintainability and contamination resistance We will provide a practical demonstration. If you are considering the introduction or update of equipment, or if you have challenges with the sensitivity and accuracy of impurity analysis, please join us. 【Title】 Nitrosamine Analysis Observation Meeting: How to streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? ~Introducing approaches for developing separation conditions~
