ザルトリウス・ステディム・ジャパン Official site

Supporting the development of advanced therapies at every stage, from research and development to application in humans.

The Recombumin product portfolio consists of commercially available, high-quality recombinant human albumin derived from both animal and human sources. Recombumin serves as a multifunctional additive, excipient, and raw material, and its stabilization properties have been validated through years of use in multiple marketed life science products.

Maximization of cell quality characteristics, assurance of reproducible results, reduction of development time.

We provide support focused on culture media, reagents, essential raw materials, biopreservation, and key cells used in gene and cell therapy. By leveraging expert support and a global manufacturing network, we offer essential resources for cells from screening to commercial production, helping to achieve your goals.

For protein production using CHO cell lines.

The Zaltorius CHO medium portfolio has been developed for the culture of Chinese hamster ovary (CHO) and other mammalian cell lines. CHO cells can be used for both stable expression and transient expression of recombinant proteins.

Introducing a medium system for protein production using the CHO system!

【Features of Standard Products】 ■ Known Chemical Composition: The exact concentrations and molecular weights of all components are known. ■ Free from Animal-Derived Components: Contains no animal-derived components and does not include any human-derived components. ■ Protein-Free: This product does not contain any proteins. ■ For Research or Further Manufacturing ■ Available as Powdered Medium ■ Available as Liquid Medium *For more details, please refer to the PDF document or feel free to contact us.

Next-generation chemical components known to support Vero cell proliferation and virus production.

4Cell NutriVero Flex 10 is a newly developed medium with known chemical components, serum-free, and free of animal-derived ingredients. It was co-developed with Intravacc, a company renowned for its R&D organization bridging the proliferation of Vero cells and virology research in 2D monolayer and 3D microcarrier suspension cultures. This medium allows for consistent results and maximum control in the virus production process.

Excellent results and flexibility with xenofree serum-free medium for lymphocyte culture!

Benefits for Four Customers 〈Performance〉 ■ Excellent Fold Expansion ■ Superior survival rate and CD8+ expression rate ■ High transduction efficiency (%) for CAR-T applications 〈Flexibility〉 ■ Excellent results with healthy PBMCs, TILs, and CAR-T applications ■ Excellent results using cells derived from cancer patients ■ Outstanding results at low seeding concentrations 〈Safety〉 ■ Elimination of serum-related risks through serum-free conditions ■ Manufactured in compliance with ISO13408 guidelines ■ Robust shipping tests 〈Simplicity〉 ■ No need for serum raw materials, storage, or purchasing ■ Short lead times ensured by Nutri-T stock at our global facilities ■ Provision of our technical support and complementary products

Xeno-free serum-free medium for hES cells and hiPS cells

■ Known chemical composition, serum-free, xenofree ■ Complete medium, ready-to-use ■ Excellent proliferation of undifferentiated hES cells and hiPS cells ■ Stable pluripotency and genotype in long-term culture ■ Thoroughly tested, widely cited in literature ■ Flexible compatibility with multiple matrices (e.g., Matrigel, laminin)

Redefining the excellence of stem cells and advancing clinical applications: a complete xenofree serum-free system for the proliferation and expansion of hMSCs.

(Product Information) 05-200-1: MSC NutriStem XF Basal Medium 05-201-1: MSC NutriStem XF Supplement Mix 05-202-1: MSC NutriStem XF Basal Medium, without Phenol Red 05-760-1: NutriCoat Attachment Solution 05-752-1: MSC Attachment Solution 05-713-1: NutriFreez D10 Cryopreservation Medium 03-078-1: Recombinant Trypsin Solution 03-079-1: Recombinant Trypsin-EDTA Solution PLTGOLD100R: PLTGold Human Platelet Lysate (Research-grade) PLTGOLD100GMP: PLTGold Human Platelet Lysate (Clinical-grade)

Completely serum-free xenofree medium enables advanced adipogenesis, osteogenesis, and chondrogenesis from hMSCs.

▪ Completely serum-free xenofree medium ▪ Verified for efficient differentiation of hMSC from various sources ▪ Simple and efficient protocol

A cost-effective and efficient standardized supplement designed to adhere human mesenchymal stem cells under serum-free and xeno-free culture conditions.

【Features】 ▪ Cell adhesion substrate containing human fibrinogen (xeno-free) ▪ Easy-to-handle stock solution ▪ Manufactured in accordance with cGMP ▪ Optimal for the proliferation and differentiation of hMSCs ▪ Long-term support for the pluripotency of hMSCs ▪ Compatible with hMSCs derived from various tissues

Serum-free, animal-derived component-free, protein-free short-term refrigerated (2-8 °C) cell preservation solution.

NutriStor refrigerated storage solution is designed to preserve highly sensitive cells without the need for repeated freeze-thaw cycles or centrifugation. It has been tested with various cell sources, including peripheral blood mononuclear cells (PBMC), chimeric antigen receptor T cells (CAR-T), and mesenchymal stromal cells (MSC), and is optimized to ensure maximum safety and high survival rates after cryopreservation.

An all-in-one solution designed for freezing and thawing cells, with a known chemical composition, particularly for cell therapy and clinical applications.

■ Simple protocol ready for immediate use ■ Fully known chemical composition medium ■ Ideal for serum-free applications ■ Free of animal components ■ Serum-free, protein-free ■ Manufactured in compliance with current GMP ■ Sterility, endotoxin, and cell-based quality control tests ■ Consistency between lots ■ Drug master file coming soon

Powerful cryopreservation medium optimized for various cells and tissues.

<Features> • Designed to minimize damage from freeze preservation • Effectively maintains cell viability, adhesion, and physiological activity • Ready-to-use, easy protocol • Can be used for cell banks and biopharmaceutical applications • Animal Component-Free, Serum-Free, Protein-Free • DMF is FDA approved • Manufactured in accordance with cGMP

Growth and transfection media suitable for various HEK cell lines.

Cell culture media and applications This is an integrated solution that supports cell thawing, proliferation, transfection, and production. There is no need to prepare a different medium for each application. This catalog provides information to help you select the media that best meets your needs.

Production medium optimized for gene introduction and viral infection.

Zaltrius's high-performance HEK medium is a comprehensive and integrated solution optimized for viral infection and transfection of a wide range of human embryonic kidney cells (HEK293) in suspension culture. Our portfolio maximizes productivity across various applications, including the production of viral vectors for gene therapy and vaccines, as well as recombinant proteins.

High-quality raw materials for gene cell therapy manufacturing.

Growth factors and cytokines are important small signaling proteins that regulate cell proliferation, differentiation, and function. CellGenix growth factors and cytokines are designed as raw materials and auxiliary materials for gene cell therapy and regenerative medicine. They are added to cell cultures to promote the proliferation and differentiation of various human cells towards target cell types, such as immune cells (e.g., T cells) and stem cells (e.g., human mesenchymal stem cells).

Next, making cell research and manufacturing easier.

Since its establishment in 1984, SoloHill has developed a wide range of microcarrier products. By combining the latest research with high-quality manufacturing facilities, SoloHill has continued to provide not only high-performance products but also technical expertise to achieve optimal experimental results for our customers. Our excellent researchers support customers in product selection, process optimization, and technology transfer to end-users.