Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Adeno-associated virus (AAV) vectors are gaining attention for their excellent suitability as vectors in gene therapy. The production of AAV vectors commonly uses transient expression system HEK cells, but the examination of their culture and production conditions is complex and time-consuming. Additionally, there is no standardized process, and product-specific characterization and safety testing are required. In this webinar, we will outline the manufacturing and process development of AAV vectors, followed by an introduction to Sartorius' culture-related solutions, including HEK media that simplify media selection, comprehensive characterization covering key evaluation items, and cell bank production. [Seminar Overview] ▪ Date: September 28 (Thursday) from 3:00 PM (approximately 45 minutes) ▪ Format: Webinar recorded broadcast [Japanese, free of charge] *We apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Viral contamination is a common challenge in the manufacturing of biopharmaceuticals. In this webinar, we will introduce virus removal-related products and validation services (Confidence Virus Clearance Services) centered around the filters that Sartorius can provide. 【Seminar Overview】 ▪ Date: September 21 (Thursday) from 3:00 PM (approximately 30 minutes) ▪ Format: Webinar recorded broadcast [Japanese, Free] *We sincerely apologize, but participation from other companies in the same industry, as well as from email addresses not affiliated with your organization, is not permitted. Thank you for your understanding.

Expectations for regenerative medicine using stem cells such as mesenchymal stem cells (MSC) and induced pluripotent stem cells (iPSC) are rising, but for industrialization, there is a need for technology to produce high-quality cells in large quantities and in a stable manner. In this seminar, we will introduce xenofree stem cell culture media that do not contain components derived from animals other than humans, as well as examples of 3D culture using our microcarriers, bioreactors, and experimental design software. We will also present HEK media used for immune cell culture media and lentivirus production as products for cell therapy, such as CAR-T. 【Seminar Overview】 ▪ Date: October 12 (Thursday) from 3:00 PM (approximately 30 minutes) ▪ Format: Webinar recorded broadcast [Japanese, Free] If you are unable to attend on the day, please register first. Later, we will send you a link to download the recorded video and related product materials. *We apologize, but participation from other companies in the same industry, as well as email addresses not associated with your organization, is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. In the pharmaceutical manufacturing environment, filtration and filter sterilization are implemented in various processes. Additionally, various types and shapes of filters have been developed and used to suit different applications and processes. The type of filter suitable for the liquid being filtered changes depending on the properties of the pharmaceutical solution, so correct knowledge is necessary for filter selection and use. Therefore, in this seminar, we will explain the basic knowledge of filters and the lineup and features of our filter products. We will also introduce and provide information on the "filter integrity testing machine" and "filtration performance testing" for filter selection. [Overview] - Date: July 20 (Thursday) from 15:00 (approximately 30 minutes) - Method: Webinar recorded broadcast [Japanese, Free] *We apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

This event has concluded. *Please note that there are currently no plans for on-demand distribution. mRNA pharmaceuticals are attracting attention as a new modality for drug discovery. Sartorius has a wide range of technologies that cover the mRNA manufacturing process, including E. coli culture, pDNA purification, IVT reactions, mRNA purification, and freeze storage. In this forum, we will provide a meaningful discussion platform centered around topics such as "pDNA|mRNA Manufacturing Processes," "Sartorius Manufacturing Platforms," and "Application Examples," inviting guest speakers to give presentations and facilitating questions and interactions from participants. Special Lecture Kazuhisa Uchida, Graduate School, Kobe University Capacity [In-person participation] 35 people *If there are many applications, a lottery will be held. [Online participation] 200 people *Please note that applications from competitors and research companies may be declined in advance.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. The Ambr 15 is an industry-standard microbioreactor system that can perform with 10-15 mL of culture medium in 24 or 48 parallel runs. After culturing, there was a challenge where the number of samples for clarification and simple purification matched the number of specimens, which became a rate-limiting step. However, the next-stage robotic device, StreamLink CC 15, from Ambr has emerged as a breakthrough. This webinar will introduce the advantages of this product, focusing on throughput, in two parts. 【Seminar Overview】 June 1, 2023 (Thursday) from 15:00 (approximately 40 minutes) Webinar recorded broadcast [Japanese, Free] *We sincerely apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. As the number of pharmaceutical companies working on gene therapy and vaccines increases, the need for culture devices for microorganisms using single-use technology is becoming more and more critical. Sartorius has developed the Biostat STR MO to meet this demand. This webinar will introduce the features and application examples of Sartorius's first single-use culture device for microorganisms, the Biostat STR MO. [Seminar Overview] Date: May 18, 2023 (Thursday) from 3:00 PM (approximately 30 minutes) Webinar recorded broadcast [Japanese, free] We will send the recorded video and the download URL for related product materials to those who registered at a later date. *We apologize, but participation from other companies in the same industry and email addresses not affiliated with your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. In recent years, with a variety of single-use culture containers of different shapes and mixing styles competing in the market, it has become very important to reflect optimized processes in larger containers and to simulate larger containers using smaller ones. BioPAT Process Insights is a browser-based software that allows for stress-free scaling from 15mL containers to 2,000L culture bags, based on experimental data conducted with a vast array of combinations. This webinar will focus on its features and convenience. [Overview] - Date: May 25 (Thursday) from 15:00 (approximately 30 minutes) - Format: Webinar recorded broadcast [Japanese, free of charge] *We kindly ask that participants from other companies in the same industry and those using email addresses not associated with their organizations refrain from participating. Thank you for your understanding.

Registration for this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. At Sartorius, we have been providing CHO cell line development services that serve as the foundation for the manufacturing of antibody and protein therapeutics. Two products developed through this service have already been launched, and over 40 molecules are currently in clinical development. This webinar will be divided into two parts to introduce this service. In Part 1, we will present the technical upgrades of this service. In Part 2, we will introduce the media products and related services that have been optimized for this service and are now available for general sale. [Seminar Overview] April 6, 2023 (Thursday) 15:00 (approximately 50 minutes) Webinar recorded broadcast [Japanese, free] *We sincerely apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. In tangential flow filtration (TFF), the processing conditions have a significant impact on the quality of the concentrated target substance. Sartorius began handling hollow fiber products for TFF two years ago. In this webinar, we will introduce the product lineup and its features, along with actual application examples. Additionally, we will share tips to improve your TFF processing conditions. [Seminar Overview] March 16, 2023 (Thursday) 15:00 (approximately 30 minutes) Webinar recorded broadcast [Japanese, free of charge] *We sincerely apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Under GMP manufacturing management, regulations require the implementation of integrity testing after product filtration, but in recent years, there has been an increasing demand for a high level of Quality Risk Management (QRM). Sartorius offers the Sartocheck 5|5 plus, a filter integrity testing device equipped with QRM capabilities that exceed those requirements, as well as the highest level of data integrity. In this webinar, we will introduce the features of Sartorius' filter integrity testing devices and the actual testing methods. 【Seminar Overview】 March 2, 2023 (Thursday) from 15:00 (approximately 35 minutes) Webinar recorded broadcast [Japanese, Free] *We sincerely apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Buffer exchange and concentration are critical processes in downstream processing. The introduction of single-use TFF (SUTFF), which can prevent cross-contamination and does not require cleaning validation, is progressing. In this webinar, we will introduce SUTFF devices for ADCs that were just launched last year, as well as SUTFF devices and TFF filters from pilot scale to production scale. 【Seminar Overview】 ▪ Date: February 16, 2023 (Thursday) from 3:00 PM (approximately 40 minutes) ▪ Format: Webinar recorded broadcast [Japanese, Free] *We sincerely apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Leaks are cited as one of the top three concerns regarding the use of single-use products. The rising cost of active pharmaceutical ingredients and the aspect of operational safety have also drawn attention to non-destructive testing before use. In this webinar, we will delve into Sartorius's concept of the integrity of single-use bags, focusing on pinhole size, water pressure, and intended use. 【Seminar Overview】 ▪ Date: February 2, 2023 (Thursday) from 3:00 PM (approximately 40 minutes) ▪ Method: Webinar recorded broadcast [Japanese, Free] If you are unable to participate on the day, please register first. We will send you the recorded video and a download URL for related product materials at a later date. *We apologize, but participation from other companies in the same industry and email addresses not associated with your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. In the biotechnology industry, monoclonal antibodies (mAb) are mainstream, but there are challenges that need to be addressed to manufacture pharmaceuticals without compromise, such as ease of use, scalability, speed, footprint, and cost. This webinar will explain how Sartobind Rapid A can resolve these bottlenecks and innovate the process. 【Seminar Overview】 ▪ Date: January 26, 2023 (Thursday) from 3:00 PM (approximately 40 minutes) ▪ Method: Webinar recorded broadcast [Japanese subtitles, free] If you are unable to participate on the day, please register first. Later, we will send you the URL for the recorded video and related product materials for download. *We apologize, but participation from other companies in the same industry and email addresses not associated with your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Freezing, storage, transportation, and thawing are important processes in the manufacturing of biopharmaceuticals. By utilizing the latest single-use technologies, we can implement freezing, thawing, and transportation processes in a robust, safe, and scalable manner. In this first webinar of 2023, we will introduce Sartorius's solution "Celsius" and its features. [Seminar Overview] ▪ Date: January 24, 2023 (Tuesday) from 3:00 PM (approximately 40 minutes) ▪ Method: Webinar recorded broadcast [Japanese, free of charge] *We sincerely apologize, but participation from companies in the same industry and email addresses other than those of your organization is not permitted. Thank you for your understanding.

Registration for this webinar has closed. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Data has long been considered one of the most important assets for companies, but there are many challenges such as a shortage of digital talent, lack of collaboration within the company, and the speed of decision-making. At Sartorius, we provide "SIMCA" as software that can be used even by those who are not data analysis experts, enabling data visualization and rapid modeling to support enhanced decision-making and data sharing. 【Seminar Overview】 ▪ Date: December 8 (Thursday) from 3:00 PM (approximately 50 minutes) ▪ Method: Webinar recorded broadcast [Japanese, Free] *We sincerely apologize, but we ask that participants from other companies in the same industry, as well as those using email addresses not associated with their organization, refrain from participating. Thank you for your understanding.

You can check the webinar hosted by Zaltorius Steadim Japan from the related materials. If you are unable to attend on the day of the event, we will share the recorded file after each webinar if you have registered. You can check the webinars available for registration from the related links. We look forward to your registration. If you have any questions, please feel free to contact us.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. There is a growing need to obtain CHO cell lines with high expression levels in as short a time as possible for the development and manufacturing of protein drugs such as antibody therapeutics. Sartorius' Cellca cell line development service has developed over 140 CHO cell lines to date, which are used for commercial or clinical trial manufacturing. In this webinar, we will introduce the technical background, service formats (contract and licensing), as well as the characterization tests and safety tests for antibody drugs, protein drugs, and various cells (gene and cell therapy, vaccines, etc.). *We sincerely apologize, but participation from email addresses other than those of your company or organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. In the complex and variable field of biopharmaceutical development, screening for the optimal culture medium requires significant time and effort. The newly launched Sartorius media for CHO and HEK cells that we will introduce supports consistent production from research to manufacturing, with known chemical composition and free from animal-derived components. Additionally, it consists of multiple types of media and feeds, allowing you to select the optimal combination tailored to individual applications and conditions. In this seminar, we will provide information on the characteristics and performance of the media, as well as samples. *We apologize, but participation from email addresses other than those of your company or organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. The development of therapeutics using viral vectors is showing strong activity, with over 30% market growth expected in the next decade. The targets for treatment are diverse, but identifying critical process parameters through process development has become an urgent issue. As the first of two webinars, we will introduce the Ambr series, a representative of process development systems in upstream processes, as well as single-use bag bioreactors up to 2000L for large-scale manufacturing, including examples of associated PAT products. *We sincerely apologize, but participation from email addresses other than those of your company or organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. AAV-based gene therapy is widely accepted and recognized in the biopharmaceutical industry. However, there are still challenges to address in order to manufacture affordable and safe AAV-based products with robust purification processes that are easy to scale up in downstream process development. In this webinar, we will explain how Sartorius can assist you in developing scalable and robust downstream purification processes for AAV using the Monolith provided by Sartorius. AAV Webinar Series 1 is here: https://srtrs.info/ios9v *We apologize, but participation from companies in the same industry and from email addresses other than those of your organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Since 2020, Sartorius has been continuously working towards process enhancement, and in February, we introduced two bioreactors using single-use bags as the completed form of the enhanced upstream process. We will present the full details of the bioreactor system that meets the needs of commercial production and automation, along with case studies, in this webinar. Related site: https://srtrs.info/r/d7yvo

The reception here has ended. Thank you for your registration. A must-see for those looking for solutions to the complex process development of gene therapy! The field of gene therapy has been receiving increasing attention in recent years, but its long and complex processes involve many considerations, requiring significant time and effort for optimization. At JAACT2022, our specialists will introduce solutions focused on process development using HEK293 cells. In the technical seminar at the venue, we will propose the latest technologies and solutions, including new products. Additionally, at our booth, we will showcase Sartorius's new products (HEK293 media sample kit | Ambr 250 perfusion) and hold demonstrations (MODDE | SIMCA). Technical Seminar Information Title: Challenges in New Modalities by Sartorius Date and Time: July 26 (Wednesday) 15:10 - 15:35 [Main Learning Content] ▪ Case study using microreactor systems (Ambr) ▪ Tools that can be used for scale-up ▪ HEK293 cell culture media system

Registration for this webinar has ended. Thank you for signing up. Sartorius will participate in the co-hosted seminar, "EthanCell Online Forum Technology Presentation Session - CPC Edition: Learning from CPC-related Companies about Various Products and Services for CPC Operations." This seminar aims to provide participants with the opportunity to learn about services and products suitable for each individual through seminars from companies in various fields related to CPC, contributing to the revitalization of regenerative medicine and research. Our company will introduce our media products used for cell culture under the title "Sartorius Media Supporting Robust and Consistent Cell Culture" starting at 14:25.

Participation in this webinar has ended. Those who wish to view it on demand can register through the details and application link. In this webinar, Marion Monstier and Sebastien Chaussin, product managers for freeze-thaw technology, will explain in detail the advantages of single-use containers compared to traditional bottles. They will also clarify important parameters to consider when validating such systems in actual processes. *Additional sessions will be held at times accommodating all time zones. We encourage you to participate and share your feedback. For those who could not attend on the day, a link to the on-demand archive will be sent to registered participants. [Main Learning Points] ▪ Advantages of single-use solutions over bottles ▪ Characteristics of single-use containers that can adapt to existing infrastructure at minimal cost ▪ Confirmation of parameters to consider when selecting single-use containers for freeze-thaw applications

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. During the COVID-19 pandemic, mRNA-based vaccines have been widely recognized by the biopharmaceutical industry and regulatory authorities. However, in downstream process development, there are challenges to address in order to manufacture affordable and safe mRNA-based vaccines using scalable and robust purification processes. We aim to introduce solutions that can be provided using our CIM monolith and develop a scalable and robust downstream purification process from pDNA to mRNA. ▪ Method of holding: Webinar recorded broadcast [in Japanese, free of charge] *We sincerely apologize, but participation from individuals using email addresses other than those from your company or organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Cellular immunotherapy has scientifically proven the efficacy of CAR-T cells in the treatment of blood cancers, and development is progressing globally. This has heightened interest in the scientific and medical communities and serves as a driving force to develop more effective and cost-efficient cellular immunotherapies. Therefore, the development of high-quality auxiliary materials such as culture media for cultivating these immune cells is crucial. To meet such needs, our company has developed the serum-free 4Cell Nutri-T Medium. Method of delivery: Webinar recorded broadcast (with Japanese subtitles, free of charge) *We sincerely apologize, but participation from email addresses other than those of your company or organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. We will provide information primarily about Sartorius' cross-flow product lineup and its features, as well as explain the single-use hardware that Sartorius has recently started to release. Additionally, we will present the full details of the TFF (Tangential Flow Filtration) hollow fiber modules that we began handling last year. Finally, we will explain how these products are integrated into the processes of the recently highlighted new modalities, such as mRNA and AAV. Related site: https://srtrs.info/r/fmc1u *We sincerely apologize, but we ask that individuals from competing companies or those using email addresses other than those of their affiliated organizations refrain from participating. Thank you for your understanding.

Registration for this webinar has closed. If you wish to view it, please contact us. We will send you the URL for the recorded video at a later date. Cryopreservation technology is becoming an increasingly essential process in the management and storage of cells, viruses, and protein products during the pharmaceutical manufacturing process. Additionally, cryopreservation technology is widely used for transportation to connect manufacturing plants that are expanding globally. Recently, the necessity for ultra-low temperature transportation and storage of Covid-19 mRNA vaccines has brought attention to cryopreservation technology. Therefore, this webinar will focus on "Considerations for Freezing Processes Using Single-Use Technology." *We apologize, but participation using email addresses other than those from your company or organization is not permitted. Thank you for your understanding.

Participation in this webinar has ended. If you wish to view it, please contact us, and we will send you the URL for the recorded video at a later date. In recent years, the rapid spread of mRNA vaccines has suddenly drawn attention to this field, but it seems that a standardized platform has yet to be established. In this webinar, we will particularly address two key points—IVT and purification—through our company's new solution-based approach. 【Main Learning Content】 ▪ Current status and challenges of mRNA pharmaceutical manufacturing processes ▪ Revolutionary purification column (Monolith) ▪ Diverse process development approaches *We kindly ask that inquiries be made using email addresses from your company or organization, as we regretfully cannot accommodate inquiries from other email addresses. Thank you for your understanding.