Sartorius Stedim Japan K.K. Official site

Process enhancement. Modify. Intensify. Amplify.

Biopharmaceutical manufacturers and CDMOs are facing the challenge of improving throughput and reducing costs to maintain competitiveness, making PI seem like a natural solution. However, the reality is that implementing the level changes that many expect is difficult. Sartorius Stedim will enhance key processes to help manufacturers align current demand with future developments, allowing them to experience the current benefits of PI while building for the future.

Introducing a medium system for protein production using the CHO system!

【Features of Standard Products】 ■ Known Chemical Composition: The exact concentrations and molecular weights of all components are known. ■ Free from Animal-Derived Components: Contains no animal-derived components and does not include any human-derived components. ■ Protein-Free: This product does not contain any proteins. ■ For Research or Further Manufacturing ■ Available as Powdered Medium ■ Available as Liquid Medium *For more details, please refer to the PDF document or feel free to contact us.

A single-use benchtop bioreactor with simple operation aimed at improving productivity.

The Ambr250 modular system has both cell culture and microbial culture capabilities, making it suitable for all types of culture applications. It is characterized by its wide range of applications, including research and development of biopharmaceuticals and recombinant production. ■ Process optimization ■ Process characterization ■ Process robustness studies for QbD research ■ Process scale-down model

Enhancing equipment performance that influences the success of cultivation! We have achieved improved flexibility.

【Other Features】 - Achieves a development approach based on Quality by Design - Reduces costs per experiment significantly by saving on facility space, funding, labor, as well as the amount of culture media and consumables - Enables better selection of clones on-site and more selection of culture media - Contributes to the optimization of faster processes *For more details, please refer to the PDF document or feel free to contact us.

A new bioreactor system for parallel operation of microbial culture or cell culture!

【Other Features】 ■ Excellent tool for process development ■ Rapid evaluation of extensive culture conditions and cell line/strain performance ■ Excellent scalability to large benchtop bioreactors ■ Reduction of infrastructure *For more details, please refer to the PDF document or feel free to contact us.

A fully automated bioreactor system for the development of high-density cell culture processes!

【Other Features】 ■ Dramatically improves the productivity of lab work, allowing more time to be dedicated to perfusion culture research. ■ By utilizing the built-in DoE (Design of Experiments) functionality, it is possible to reach accurate results with fewer experiments, contributing to cost reduction compared to experiments conducted in a bench-top bioreactor. ■ In perfusion culture, a wide range of important parameters such as cell density, cross-flow rate, perfusion rate, bleed volume, bleed frequency, and type of hollow fiber can be optimized. ■ Demonstrates maximum strength in research aimed at perfusion culture using single-use bag culture systems and bioreactor STR. *For more details, please refer to the PDF document or feel free to contact us.

Bioreactor system for cell line development and process optimization.

■ The new features improve the performance of applications such as the following: - Clone selection - Optimization of culture media and feeds - High-density culture processes - Media exchange and passaging in cell therapy applications ■ The new variable deck reduces operator downtime and improves operator efficiency ■ The new Amber clone selection software makes the best clone decision process easier ■ The new Generation 2 liquid handler enables faster and more precise operations, capable of complex tasks such as liquid mixing and addition in multifactorial design of experiments (DoE) ■ Ambr15 is the industry-standard micro-bioreactor system used in research facilities worldwide ■ The addition of metabolite analysis equipment enables a development approach in accordance with Quality by Design (QbD) ■ Ambr15 significantly reduces the amount of culture media and consumables, thereby lowering the cost per experiment, in addition to saving on facility space, funding, and labor ■ Ambr15 contributes to better clone selection on-site, more media selection, and faster process optimization

A multi-talented benchtop bioreactor that supports the research and development of biopharmaceuticals.

【Cultivation Targets】 ■ Mammalian Cells ■ Insect Cells ■ Microorganisms ■ Yeast ■ Fungi ■ Plant Cells *For more details, please refer to the PDF document or feel free to contact us.

A single-use bioreactor system that dramatically enhances speed, quality, and productivity from process development to scale-up.

Large-scale single-use bioreactor system ■ Equipped with the analysis tool "BioPAT(R)" and the automation platform "BIOBRAIN" ■ Compatible with volumes from 12.5 L to 2000 L ■ Enhanced bioreactor operation