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[Analysis Case] Observation of Fine Surface Morphology of Three-Dimensional Cultured Human Skin

C0496.jpg

[Analysis Case] Observation of Fine Surface Morphology of Three-Dimensional Cultured Human Skin

C0496.jpg
C0496.jpg

Visualization of nanoscale roughness on the skin surface using AFM.

In recent years, the development of alternative methods to animal testing for the efficacy and safety testing of pharmaceuticals and cosmetics has been progressing, with particular attention being paid to testing methods using three-dimensional cultured skin. In this case study, a percutaneous absorption test of a cosmetic (lotion) was conducted using three-dimensional cultured human skin, which was measured using AFM (Atomic Force Microscopy). This allows for a visual evaluation of the microstructure of the skin surface, and it is also possible to quantitatively assess the roughness of any specific area. By measuring under atmospheric conditions, it is possible to observe the samples while minimizing alterations that would occur under vacuum conditions.

Related Link - https://www.mst.or.jp/casestudy/tabid/1318/pdid/43…

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Analysis of biotechnology, pharmaceuticals, and cosmetics.

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[Analysis Case] Observation of Micro-Shape on the Surface of Three-Dimensional Cultured Human Skin_C0496

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