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Differentiation of mass spectrometry methods for solid sample surfaces

B0266.jpg

Differentiation of mass spectrometry methods for solid sample surfaces

B0266.jpg
B0266.jpg

It is effective to differentiate between the two methods according to the purpose components and the size of the imaging field.

TOF-SIMS and MALDI-MS, which are representative mass spectrometry methods for solid sample surfaces, both enable qualitative analysis and imaging analysis. TOF-SIMS, which utilizes hard ionization methods, can detect inorganic and organic components with masses up to several hundred with high sensitivity. On the other hand, MALDI-MS, which employs soft ionization methods, can detect polymers in the range of thousands to tens of thousands. Additionally, the spatial resolution of the images also varies depending on the diameter of the irradiation beam.

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Differentiation of Mass Spectrometry Methods for Solid Sample Surfaces_B0266

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