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Mass array method: A gene analysis method using mass spectrometry.

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Mass array method: A gene analysis method using mass spectrometry.

Genetic analysis is a method that reads the nucleotide sequences of DNA to investigate gene mutations and functions.

In this method, the differences in the mass of bases are analyzed using MALDI-TOF-MS to determine the DNA base sequence. This allows for the detection of SNPs (single nucleotide polymorphisms), INDELs (insertions/deletions), CNVs (copy number variations), and more. It is characterized by the ability to analyze a large number of samples and detect a wide range of genes at once. - Multiplex PCR and MALDI-TOF-MS enable simultaneous analysis of up to 40 mutation sites. - Mass spectrometry specialized for the detection of bases (A/T/G/C) is possible. - A variety of analytical tools are available that have been pre-designed to detect target genes based on specific purposes. - Custom designs for analytical tools are also possible.

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Applications/Examples of results

■Target Gene Designed Analysis Tool - Genetic polymorphism testing of drug metabolism enzymes, including 20 genes such as CYP2D6 / CYP2C19 - Various cancers (lung cancer, colorectal cancer, melanoma) - Mutation analysis of the novel coronavirus and more ■Original Design Analysis Tool Freely designed for any SNPs, etc. <Examples of Use> - Disease-related gene analysis, human constitution/genetic testing - Cell quality assessment, livestock parentage testing - Crop variety identification, bacterial testing in food (such as E. coli O157)

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