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Liquid Chromatography-Fourier Transform Mass Spectrometry

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Liquid Chromatography-Fourier Transform Mass Spectrometry

High-resolution and high-precision analysis is possible with the OrbitrTM mass spectrometer (HRMS).

Liquid chromatography (LC) is a method for separating components in a liquid based on differences in the interactions between the stationary phase and the mobile phase. Liquid chromatography-Fourier transform mass spectrometry (LC-FTMS) utilizes a Fourier transform mass spectrometer to detect components separated by LC, allowing for the acquisition of precise mass information to four decimal places with high resolution. Therefore, when focusing on secondary isotope ions, it is possible to separate peaks derived from 13C and 34S, enabling more accurate composition estimation with higher resolution and precision compared to quadrupole or time-of-flight mass spectrometers. Additionally, it is possible to perform multi-stage MS/MS (MSn) using an ion trap, allowing for the acquisition of fragment ions for specific ions. Various methods can be combined for MSn fragmentation, enabling accurate qualitative analysis of unknown compounds by performing MSn in combination.

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- Analysis of the components contained in cleaning solutions, surfactants, etc. - Qualitative analysis of biomaterials in agriculture, biochemistry, and biotechnology fields - Qualitative analysis of additives in polymers - Qualitative analysis of organic EL materials - Analysis of trace impurities in solutions - Extractables and leachables (E&L) testing - Extraction of differences between samples using multivariate analysis

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Liquid Chromatography - Fourier Transform Mass Spectrometry_B0264

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